4-Chlorophenylguanidine hydrochloride
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
4-Chlorophenylguanidine hydrochloride是一种强效的选择性尿激酶（urokinase）抑制剂[1]。
尿激酶是一种丝氨酸蛋白酶。其主要的生理底物是血纤维蛋白溶酶原，是血纤维蛋白溶酶的无活性形式。尿激酶在血管性疾病和肿瘤中起重要作用。
4-Chlorophenylguanidine hydrochloride抑制尿激酶和胰蛋白酶的活性，Ki值分别为6.07 μM和120 μM[1]。
参考文献：
[1]. Yang H, Henkin J, Kim KH, et al. Selective inhibition of urokinase by substituted phenylguanidines: quantitative structure-activity relationship analyses. J Med Chem, 1990, 33(11): 2956-2961.
| Physical Appearance | White crystalline solid |
| Storage | Store at RT |
| M.Wt | 206.07 |
| Cas No. | 14279-91-5 |
| Formula | C7H8ClN3·HCl |
| Solubility | Soluble to 100 mM in H2O |
| Chemical Name | 2-(4-chlorophenyl)guanidine;hydrochloride |
| SDF | Download SDF |
| Canonical SMILES | C1=CC(=CC=C1N=C(N)N)Cl.Cl |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
化学结构
