HER2
HER2 is a member of the epidermal growth factor. It initiates the EGF downstream cascade by forming a heterodimer with other ligand-bound EGF receptor. It is associated with breast and ovarian cancers.
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B5827 Poziotinib中文名: 波齐替尼Summary: pan-HER抑制剂 -
B1544 Tyrphostin AG 879Summary: HER2 抑制剂 -
B1543 Mubritinib (TAK 165)中文名: 木利替尼Target: ErbBSummary: HER2/ErbB2有效抑制剂 -
A8528 TAK-285Target: EGFR|HER2Summary: HER2/EGFR(HER1)抑制剂 -
A8322 Neratinib (HKI-272)1 Citation中文名: 来那替尼Target: EGFRSummary: HER2/EGFR抑制剂 -
A1835 Pelitinib (EKB-569)中文名: 培利替尼Summary: 有效的EGFR不可逆抑制剂 -
A2412 CP-724714Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1RSummary: 有效的HER2选择性抑制剂 -
A8247 Afatinib (BIBW2992)1 Citation中文名: 阿法替尼Target: EGFRSummary: EGFR/ HER2抑制剂 -
A8218 Lapatinib2 Citation中文名: 拉帕替尼Target: ErbBSummary: EGFR/HER2抑制剂 -
A3967 Lapatinib Ditosylate中文名: 二苯磺酸拉帕替尼Target: EGFR|ErbB-2Summary: EGFR / HER2抑制剂