Alzheimer
Alzheimer
Alzheimer’s disease (AD), a neurodegenerative disorder, is the most common cause of progressive dementia. Two microscopic characteristics of AD are extracellular amyloid plaques and intracellular neurofibrillary tangles. Amyloid β peptide (Aβ), derived from amyloid precursor protein (APP) by sequential protein cleavage, and other metabolites deposit around neurons and form amyloid plaques, which contribute to the disease’s pathogenesis. The neurofibrillary tangles are formed by the aggregation of phosphorylated tau proteins. Under pathogenic conditions, tau accumulates in dendritic spines and interferes with neurotransmission. The Aβoligomer promotes tau enrichment and facilitates disease progress. read more
- A1053 amyloid A protein fragment [Homo sapiens]Summary: 血浆中与HDL相关的载脂蛋白
- A1031 Myelin Basic Protein (68-82), guinea pigSummary: 对神经髓鞘的形成具有重要作用。
- A1005 Beta-Sheet Breaker Peptide iAβ5Summary: 抑制淀粉样蛋白生成的多肽
- A1004 Amyloid Precursor C-Terminal PeptideSummary: 用于β淀粉样蛋白的产生
- A1003 Amyloid β-Protein (1-15)Summary: β淀粉样蛋白(1-15),淀粉样蛋白的主要成分。
- A1002 Beta-Amyloid (1-11)Summary: 淀粉样变性肽
- A1131 COG 133Summary: 载脂蛋白E(ApoE)模拟肽
- A1124 Amyloid Beta-Peptide (1-40) (human)1 CitationSummary: β淀粉样蛋白
- A1123 Amyloid Beta-Peptide (12-28) (human)Summary: β淀粉样蛋白肽
- A1040 Myelin Basic Protein (87-99) GUINEA PIG, HUMANSummary: 脑炎肽