Dehydrogenase
Dehydrogenases, belonging to the class of oxidoreductases which catalyze donor-acceptor reactions to transfer electron molecules from the oxidant to the reluctant, are a diverse group of enzymes that are able to transfer one or more hydrides (H-) from a substrate to an electron acceptor, such as nicotinamide adenine dinucleotide (NAD+), nicotinamide adenine dinucleotide phosphate (NADP+) or Riboflavin, through oxidation and reduction. Three commonly studied dehydrogenase enzymes include alcohol dehydrogenase (ADH) which catalyzes the reduction of acetylaldehyde to ethanol in plant cells, succinate dehydrogenase which oxidizes succinate to fumarate, and lactate dehydrogenase which catalyzes the reversible oxidation of lactate to pyruvate.
- C5478 NCT-502Summary: 3-磷酸甘油酸脱氢酶(PHGDH)抑制剂
- C5603 A-771726中文名: 特立氟胺Summary: 二氢乳清脱氢酶抑制剂
- C4845 PHGDH-inactiveSummary: 3-磷酸甘油酸脱氢酶(PHGDH)抑制剂NCT-502和NCT-503的无活性类似物
- C4671 Inosine-5'-monophosphate (sodium salt hydrate)Summary: IMP脱氢酶(IMPDH)的底物
- C4497 6-AminonicotinamideSummary: 6-磷酸葡萄糖酸脱氢酶抑制剂
- C3853 NCT-503Summary: 3-磷酸甘油酸脱氢酶(PHGDH)抑制剂
- C3535 Piericidin A中文名: 粉蝶霉素ASummary: 线粒体复合体I抑制剂
- C3039 STK393606Summary: NAD+依赖性I型15-羟基PGDH的竞争性抑制剂
- B7824 ML390Summary: 人DHODH抑制剂
- B7805 AG-120Summary: 突变IDH1抑制剂