HDAC
Histone deacetylases (HDACs), known for their ability to target histones as well as more than 50 non-histone proteins, are classified into three major classes according to their homology to yeast proteins, including class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC7 and HDAC9) and class IV (HDAC11). HDAC inhibitors, a large group of compounds that is able to induce the accumulation of acetylated histones as well as non-histone proteins, are divided into several structural classes including hydroxamates, cyclic peptides, aliphatic acids and benzamides. HDAC inhibitors have been investigated for their efficacy as anticancer agents in the treatment of a wild range of cancers.
- C5851 MI-192Summary: 组蛋白去乙酰化酶(HDACs)抑制剂
- C4327 CBHASummary: HDAC抑制剂
- C4305 HNHASummary: HDAC抑制剂
- C3606 NullscriptSummary: HDAC抑制剂scriptaid的阴性对照
- B5882 ORY-10011 CitationSummary: KDM1A抑制剂
- B4988 BRD739541 CitationSummary: HDAC抑制剂
- B4856 CAY10603Target: Histone Deacetylases (HDACs)Summary: HDAC6抑制剂
- B4794 Santacruzamate A (CAY10683)Target: Histone Deacetylases (HDACs)Summary: HDAC抑制剂
- B1251 Valproic acid中文名: 丙戊酸Target: Histone Deacetylases (HDACs)Summary: HDAC1抑制剂
- B1141 Varenicline HydrochlorideSummary: α4β2烟碱受体激动剂