Protein Ser/Thr Phosphatases
Protein Ser/Thr phosphatases, belonging to the superfamily of protein phosphatases, are a diverse group of phosphatases that catalyze dephosphorylation and specifically remove phosphate groups from phosphorylated Ser and Thr residues within their substrates. Protein Ser/Thr phosphatases are comprised of two distinct families of phosphatases, including PPP phosphatases and PPM (or PP2C-related) phosphatases, which are coded by two unrelated gene families but share remarkably similar architecture of catalytic domains. PPP family was initially divided into two classes, type-I phosphatases (PP1) and type-2 phosphatases (PP2) consisting of PP2A, PP2B and PP2C isoforms. Novel protein phosphatases, such as PP4, PP5, PP6 and PP7, are also included in PPP family. PPM family is comprised of a number of Mg2+-dependent phosphatases encoded by different genes, which are structurally related to PP2C.
- C4614 bpV(HOpic) (potassium salt, technical grade)Summary: 蛋白酪氨酸磷酸酶(PTPs)抑制剂
- C4401 PTP Inhibitor IVSummary: PTP抑制剂
- C4347 β-Glycerophosphate (sodium salt hydrate)中文名: β-甘油磷酸钠盐水合物Summary: 蛋白磷酸酶抑制剂
- C3996 PRL-3 InhibitorSummary: 再生肝脏蛋白磷酸酶-3(PRL-3)抑制剂
- C3898 Cantharidic Acid (sodium salt)Summary: PP1和PP2A抑制剂
- C3607 PTP Inhibitor I中文名: PTP抑制剂一Summary: 酪氨酸磷酸酶(PTP)抑制剂
- C3591 PTP Inhibitor II中文名: PTP抑制剂二Summary: 蛋白酪氨酸磷酸酶(PTP)抑制剂
- B5970 Sanguinarine chloride中文名: 盐酸血根碱Summary: PP2C和MKP-1抑制剂
- A8708 Sephin11 CitationTarget: phosphatasesSummary: PPP1R15A抑制剂
- B4846 LB-100Summary: 蛋白磷酸酶2A(PP2A)抑制剂