vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus]
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
维生素D结合蛋白（DBP）是一种多功能的、高表达的多态性血清蛋白[1,2]。自1959年鉴定之后，发现维生素D结合蛋白的许多重要功能，包括维生素D代谢物的转运、免疫系统和宿主防御[3]。分子量范围、外观的时间过程以及膳食锶的效果表明，这类新出现的蛋白（条带C）可能代表着响应于维生素D的钙结合蛋白的形成。使用色谱纯化来自大鼠肠的钙结合蛋白，结果表明，该蛋白（条带C）最可能是钙结合蛋白。在大鼠钙结合蛋白的最终纯化过程中，在凝胶上可观察到主要的污染蛋白（条带A），这种蛋白是预先存在的，可能是钙结合蛋白的前体[4]。
参考文献：
[1] N.E. Cooke, J.G. Haddad, Vitamin D binding protein (Gc-globulin), Endocr. Rev., 10 (1989), pp. 294–307
[2] N.E. Cooke, J.G. Haddad, Vitamin D binding protein (Gc-globulin): update 1995, A. Negro-Vilar, D.D. Bikle (Eds.), Endocrine Reviews Monographs: 4. Hormonal Regulation of Bone Mineral Metabolism, The Endocrine Society (1995), pp. 125–128
[3] Peter White, Nancy Cooke, “The Multifunctional Properties and Characteristics of Vitamin D-binding Protein”,Volume 11, Issue 8, 1 October 2000, Pages 320–327.
[4] H. F. DeLuca , D. Drescher, Possible precursor of vitamin D-stimulated calcium binding protein in rats, Biochemistry, 1971, 10 (12), pp 2308–2312 , DOI: 10.1021/bi00788a020, Publication Date: June 1971.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 1254.44 |
| Formula | C54H95N17O17 |
| Synonyms | H2N-His-Leu-Ser-Leu-Leu-Thr-Thr-Leu-Ser-Asn-Arg-OH |
| Solubility | ≥125.4 mg/mL in DMSO; ≥57.6 mg/mL in H2O; ≥59.1 mg/mL in EtOH |
| SDF | Download SDF |
| Canonical SMILES | NC(CC1=CN=CN1)C(NC(CC(C)C)C(NC(CO)C(NC(CC(C)C)C(NC(CC(C)C)C(NC(C(C)O)C(NC(C(NC(CC(C)C)C(NC(CO)C(NC(CC(N)=O)C(NC(CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)C(O)C)=O)=O)=O)=O)=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
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