HDAC - Cell Experiments
Histone deacetylases (HDACs), known for their ability to target histones as well as more than 50 non-histone proteins, are classified into three major classes according to their homology to yeast proteins, including class I (HDAC1, HDAC2, HDAC3 and HDAC8), class II (HDAC4, HDAC5, HDAC7 and HDAC9) and class IV (HDAC11). HDAC inhibitors, a large group of compounds that is able to induce the accumulation of acetylated histones as well as non-histone proteins, are divided into several structural classes including hydroxamates, cyclic peptides, aliphatic acids and benzamides. HDAC inhibitors have been investigated for their efficacy as anticancer agents in the treatment of a wild range of cancers.
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- B1251 Valproic acid中文名: 丙戊酸Target: Histone Deacetylases (HDACs)Summary: HDAC1抑制剂
- A8803 RGFP9664 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC3抑制剂
- A8547 Tubastatin A HCl1 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC6(组蛋白去乙酰化酶6)抑制剂
- A4498 SBHA1 CitationTarget: Histone Deacetylases (HDACs)Summary: 细胞渗透性HDAC1/HDAC3抑制剂
- A4501 Tubacin3 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC6有效的、选择性、可逆的、细胞通透性的抑制剂。
- A4497 PyroxamideTarget: Histone Deacetylases (HDACs)Summary: HDAC1抑制剂
- A4496 NSC 3852Target: Histone Deacetylases (HDACs)Summary: HDAC抑制剂
- A3761 RG2833Target: HDACSummary: 脑渗透性HDAC抑制剂
- A3348 Daminozide中文名: 丁酰肼Target: KDM|PHFSummary: KDM2A抑制剂
- A4101 Tubastatin A6 CitationTarget: Histone Deacetylases (HDACs)Summary: HDAC6抑制剂