Signaling Pathways - Insulin-like growth factor receptors(IGFRs) - PTK - HDM2 ubiquitin ligase - Smoothened
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B2266 LDE225 (NVP-LDE225,Erismodegib)1 Citation中文名: 索尼德吉Target: SmoothenedSummary: Smoothened抑制剂 -
B3283 PF-04449913中文名: 格拉吉布Target: SmoothenedSummary: Smoothened拮抗剂 -
A8340 Cyclopamine1 Citation中文名: 环巴胺Target: SmoothenedSummary: Hedgehog (Hh)信号抑制剂 -
A2689 Butein中文名: 紫铆因，紫铆查尔酮Target: Src|STAT|EGFR|Angiotensin-Converting Enzymes (ACEs)|5-Lipoxygenases|PTK|enoyl-acyl-carrier protein reductaseSummary: 蛋白激酶抑制剂 -
A2198 Genistein中文名: 金雀异黄酮，染料木素Target: Estrogen and Related Receptors|PPAR|PTKSummary: ER agonist -
A3543 LDE225 DiphosphateTarget: SmoothenedSummary: Smo拮抗剂 -
A3258 BMS-833923Target: SmoothenedSummary: Smoothened抑制剂 -
A3209 AXL1717中文名: 鬼臼毒素Target: Insulin-like growth factor receptors(IGFRs)Summary: IGF-1R抑制剂，口服有效。 -
A4204 JNJ-26854165 (Serdemetan)1 CitationTarget: p53|HDM2 ubiquitin ligaseSummary: P53激活剂，阻断Mdm2-p53相互作用。