Signaling Pathways - p53 - Acyl coenzyme A: cholesterol acyltransferases - CRM1 - Farnesoid X receptors (FXRs)
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B4888 Obeticholic Acid2 Citation中文名: 奥贝胆酸Target: Farnesoid X receptors (FXRs)Summary: FXR激动剂 -
B1528 XL335Target: Farnesoid X receptors (FXRs)Summary: FXR激动剂 -
B1463 KPT-276Target: nuclear export|CRM1Summary: CRM1抑制剂 -
A8463 Lithocholic Acid中文名: 石胆酸Target: Farnesoid X receptors (FXRs)|Vitamin D receptors (VDRs)|Pregnane X receptor(PXR)Summary: 维生素D受体PXR和FXR的激活剂 -
A4482 Pifithrin-μ1 CitationTarget: Autophagy|p53|HSP70Summary: p53结合抑制剂，抗凋亡。 -
A4483 PRIMA-1Target: p53Summary: BAX抑制剂 -
A4481 PhiKan 083Target: p53Summary: P53稳定剂 -
A4318 Avasimibe中文名: 阿伐麦布Target: Acyl coenzyme A: cholesterol acyltransferasesSummary: ACAT抑制剂 -
A4203 Tenovin-1Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21Summary: SIRT2 抑制剂，p53激活剂 -
A4204 JNJ-26854165 (Serdemetan)1 CitationTarget: p53|HDM2 ubiquitin ligaseSummary: P53激活剂，阻断Mdm2-p53相互作用。