Proteases - Dipeptidyl-peptidase II - MMP
Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.
- B5780 UAMC 00039 dihydrochlorideTarget: Dipeptidyl-peptidase IISummary: 二肽基肽酶II(DPP-II)抑制剂
- B4686 TAPI-12 CitationTarget: MMPSummary: TACE/ADAM17抑制剂
- A4442 WAY 170523Target: MMPSummary: MMP-13抑制剂
- A4432 ARP 1001 CitationTarget: MMPSummary: MMP-2抑制剂
- A4051 NSC 4050201 CitationTarget: MMPSummary: MT1-MMP抑制剂
- A4050 GM 60012 Citation中文名: 伊洛马司他Target: MMPSummary: 广谱MMP抑制剂
- A4049 Marimastat1 Citation中文名: 马立马司他Target: MMPSummary: MMPs抑制剂