Membrane Transporter/Ion Channel - CFTR - Ionophores - Na /K ATPases
Ion channels are pore-forming membrane proteins which allow the flow of ions across the membrane. The ion channels can be broadly grouped into six families including calcium channels, chloride channels, potassium channels, sodium channels, gap junction proteins and porins. Not all ion channels are gated, such as certain type of K+ and Cl– channels, transient receptor potential superfamily of cation channels, the ryanodine receptors and the IP3 receptors, but most Na+, K+, Ca2+ and some Cl– channels are all gated by voltage. Ligand-gated channels are regulated in response to ligand binding (e.g. neurotransmitters signaling). These ligand-gated neurotransmitter receptors are known as ionotropic receptors. Various neurotransmitters couple to ionotropic receptors such as glutamate, acetylcholine, glycine, GABA, and serotonin.
- B7388 Valinomycin中文名: 缬氨霉素Target: IonophoresSummary: 钾离子特异性转运体
- B7705 Lithium carbonate中文名: 碳酸锂Target: Na /K ATPasesSummary: Na+/K+ ATPase抑制剂
- B1087 GlyH-101Target: CFTRSummary: CFTR Inhibitor II
- A8637 IOWH-032Target: CFTRSummary: CFTR抑制剂
- A8351 VX-809中文名: 鲁玛卡托Target: CFTRSummary: CFTR调节剂
- A2664 VX-661Target: CFTRSummary: F508del CFTR校正子
- A3507 Istaroxime1 CitationTarget: Na /K ATPasesSummary: Na+/K+ ATPase的抑制剂