Membrane Transporter/Ion Channel - Cell Experiments
Ion channels are pore-forming membrane proteins which allow the flow of ions across the membrane. The ion channels can be broadly grouped into six families including calcium channels, chloride channels, potassium channels, sodium channels, gap junction proteins and porins. Not all ion channels are gated, such as certain type of K+ and Cl– channels, transient receptor potential superfamily of cation channels, the ryanodine receptors and the IP3 receptors, but most Na+, K+, Ca2+ and some Cl– channels are all gated by voltage. Ligand-gated channels are regulated in response to ligand binding (e.g. neurotransmitters signaling). These ligand-gated neurotransmitter receptors are known as ionotropic receptors. Various neurotransmitters couple to ionotropic receptors such as glutamate, acetylcholine, glycine, GABA, and serotonin.
- B1867 Verapamil HCl1 Citation中文名: 盐酸维拉帕米Target: Voltage-gated Calcium Channels (CaV)Summary: L-型钙通道阻断剂
- B1087 GlyH-101Target: CFTRSummary: CFTR Inhibitor II
- B1989 Nisoldipine中文名: 尼索地平Target: Voltage-gated Calcium Channels (CaV)Summary: 钙通道阻断剂
- B2193 Mitiglinide Calcium中文名: 米格列奈钙Target: Inward Rectifier Potassium (Kir) ChannelsSummary: 钾通道抑制剂
- B1531 (R)-baclofen中文名: (R)-巴氯芬Target: GABAB ReceptorsSummary: GABA受体激动剂
- B1627 (-)-MK 801Target: NMDA ReceptorsSummary: 有效的NMDA选择性拮抗剂
- B2100 HC-030031Target: TRPASummary: TRPA1通道阻断剂
- B2277 A-803467Target: Voltage-gated Sodium (NaV) ChannelsSummary: NaV1.8通道阻断剂
- B1055 IcilinTarget: TRP ChannelSummary: TRPM8/ hENaCδ激动剂
- B3041 BTB06584Target: F1 Fo-ATPaseSummary: F1F0 ATP合酶抑制剂