Membrane Transporter/Ion Channel - Monocarboxylate transporters (MCTs) - F1 Fo-ATPase - mitochondrial pyruvate carrier (MPC) - GABAA receptor
Ion channels are pore-forming membrane proteins which allow the flow of ions across the membrane. The ion channels can be broadly grouped into six families including calcium channels, chloride channels, potassium channels, sodium channels, gap junction proteins and porins. Not all ion channels are gated, such as certain type of K+ and Cl– channels, transient receptor potential superfamily of cation channels, the ryanodine receptors and the IP3 receptors, but most Na+, K+, Ca2+ and some Cl– channels are all gated by voltage. Ligand-gated channels are regulated in response to ligand binding (e.g. neurotransmitters signaling). These ligand-gated neurotransmitter receptors are known as ionotropic receptors. Various neurotransmitters couple to ionotropic receptors such as glutamate, acetylcholine, glycine, GABA, and serotonin.
- B3041 BTB06584Target: F1 Fo-ATPaseSummary: F1F0 ATP合酶抑制剂
- A3899 UK-50991 CitationTarget: Monocarboxylate transporters (MCTs)|mitochondrial pyruvate carrier (MPC)Summary: MCTs和MPC抑制剂
- A3401 Etifoxine hydrochloride中文名: 艾替伏辛盐酸盐Target: GABAA receptorSummary: GABAA受体增强剂
- A3185 AR-C155858Target: Monocarboxylate transporters (MCTs)Summary: MCT1和MCT2抑制剂