Membrane Transporter/Ion Channel - Na /H Exchangers (NHEs) - Na /K ATPases - TRP Channel
Ion channels are pore-forming membrane proteins which allow the flow of ions across the membrane. The ion channels can be broadly grouped into six families including calcium channels, chloride channels, potassium channels, sodium channels, gap junction proteins and porins. Not all ion channels are gated, such as certain type of K+ and Cl– channels, transient receptor potential superfamily of cation channels, the ryanodine receptors and the IP3 receptors, but most Na+, K+, Ca2+ and some Cl– channels are all gated by voltage. Ligand-gated channels are regulated in response to ligand binding (e.g. neurotransmitters signaling). These ligand-gated neurotransmitter receptors are known as ionotropic receptors. Various neurotransmitters couple to ionotropic receptors such as glutamate, acetylcholine, glycine, GABA, and serotonin.
- B7389 EIPA3 CitationTarget: Na /H Exchangers (NHEs)Summary: TRPP3通道抑制剂
- B7705 Lithium carbonate中文名: 碳酸锂Target: Na /K ATPasesSummary: Na+/K+ ATPase抑制剂
- B1055 IcilinTarget: TRP ChannelSummary: TRPM8/ hENaCδ激动剂
- A1174 AMG-517Target: TRP ChannelSummary: TRPV1拮抗剂
- A3507 Istaroxime1 CitationTarget: Na /K ATPasesSummary: Na+/K+ ATPase的抑制剂