Apoptosis Inducers - Histone Deacetylases (HDACs) - FPTase
Apoptosis, a programmed cell death to eliminate damaged or abnormal cells, is a highly organized physiological process characterized by condensation of nuclear heterochromatin, cell shrinkage and loss of positional organization of organelles in the cytoplasm. Apoptosis inducers are a collection of compounds that are capable of inducing apoptosis in cells. Apoptosis has been extensively studied in numerous researches, where induction of apoptosis has been associated with a variety of events, including activation of p53 gene, transcription factor NF-κB or caspases. Apoptosis inducers have the potential to be incorporated into the management and therapy or prevention of cancer for their ability to induce apoptosis in cancer cells.
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- A3335 Curcumin1 Citation中文名: 姜黄素Target: Histone Deacetylases (HDACs)|Nrf2|Histone Acetyltransferases (HATs)|TyrosinasesSummary: Tyrosinase(酪氨酸酶)抑制剂
- A3327 Costunolide中文名: 木香烃内酯Target: FPTase|TelomerasesSummary: BMM分化抑制剂
- A8176 Apicidin2 CitationTarget: Histone Deacetylases (HDACs)Summary: 有效的HDAC抑制剂