Membrane Transporter/Ion Channel - Delayed rectifier outward potassium current (IKr) - benzodiazepine receptor - alkaline phosphatases
Ion channels are pore-forming membrane proteins which allow the flow of ions across the membrane. The ion channels can be broadly grouped into six families including calcium channels, chloride channels, potassium channels, sodium channels, gap junction proteins and porins. Not all ion channels are gated, such as certain type of K+ and Cl– channels, transient receptor potential superfamily of cation channels, the ryanodine receptors and the IP3 receptors, but most Na+, K+, Ca2+ and some Cl– channels are all gated by voltage. Ligand-gated channels are regulated in response to ligand binding (e.g. neurotransmitters signaling). These ligand-gated neurotransmitter receptors are known as ionotropic receptors. Various neurotransmitters couple to ionotropic receptors such as glutamate, acetylcholine, glycine, GABA, and serotonin.
- B6401 PK 111951 CitationTarget: benzodiazepine receptorSummary: 外周苯二氮卓拮抗剂
- A8417 Dofetilide2 Citation中文名: 多非利特Target: Delayed rectifier outward potassium current (IKr)Summary: 钾通道抑制剂
- A8524 Sodium Orthovanadate中文名: 正钒酸钠Target: Protein Tyrosine Phosphatases|alkaline phosphatases|ATPasesSummary: PTP抑制剂