Hypoxanthine
| 规格 | 价格 | 货期 | 数量 |
|---|---|---|---|
| 50mg | ￥318.00 | 现货 |
特色产品
- 适用于流式细胞仪和荧光显微镜检测
- 准确区分活细胞/凋亡细胞/坏死细胞
- 用于免疫印迹和质谱分析等后续操作
- 适用于30 KDa-130 KDa大小的蛋白
- 对细胞无毒性
- 步骤更简单，无需有机溶剂
- 可将信号灵敏度提高100倍
- 同时保持稳定的特异性和分辨率
- 提供更高的转录效率并抑制免疫激活
- 使用5-moUTP和Cy5-utp修饰
- 优异的扩增效率、可重复性和稳定性
- 卓越的灵敏度和准确性，操作简单
- 优化的缓冲液和T7 RNA聚合酶混合物
- 20 μL反应体系可获得更高的RNA产量
产品描述
Hypoxanthine is a natural purine derivative, with potential to be used as a free radical generator. Hypoxanthine seems to play a role in posthypoxic reoxygenation cell injury via oxygen radical production, and is thus involved in the pathogenesis of many diseases. Hypoxanthine also modulates a variety of other processes because it can react with benzodiazepine receptors and inhibit phosphodiesterase in the brain. Hypoxanthine has been reported to be used as an indicator of hypoxia.
References:
1. Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatric Research, 1988, 23(2): 143-150.
2. Skolnick P, Marangos PJ, Goodwin FK, et al. Identification of inosine and hypoxanthine as endogenous inhibitors of [3H] diazepam binding in the central nervous system. Life Sciences, 1978, 23(14): 1473-1480.
产品性质
| 物理外观 | A solid |
| CAS号 | 68-94-0 |
| 分子式 | C5H4N4O |
| 分子量 | 136.11 |
| 溶解度 | insoluble in EtOH; insoluble in H2O; ≥1.36 mg/mL in DMSO with ultrasonic; ≥5.89 mg/mL in EtOH with ultrasonic |
| SMILES | O=C1N=CNc2c1[nH]cn2 |
| 存储条件 | -20°C |
| 运输条件 | 蓝冰 |
产品应用 (实验数据来自文献，APExBIO并未验证，仅供参考)
IC50和靶点
| 生物活性描述 | 次黄嘌呤是一种嘌呤衍生物，是一种潜在的自由基生成物，可用作缺氧指标。 |
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