Finasteride acetate
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Finasteride acetate(MK-906\Proscar和Propecia)是5α还原酶的特异性抑制剂,被合成用于治疗良性前列腺增生(BPH)和男性型脱发(MPB)[1].
在大鼠和狗的药理实验中,Finasteride acetate(MK-906\Proscar和Propecia)显著降低前列腺组织中的二氢睾酮浓度而没有显示副作用.此外,Finasteride acetate抑制5α还原酶活性,从而显著降低二氢睾酮水平.临床试验表明,Finasteride acetate也可以减少前列腺体积[1].此外,在大鼠前列腺组织的体外实验中,Finasteride acetate抑制葡萄糖醛酸转移酶[2].
参考文献：
[1] Stoner E. The clinical development of a 5 alpha-reductase inhibitor, finasteride. J Steroid Biochem Mol Biol. 1990 Nov 20;37(3):375-8.
[2] Rittmaster RS1, Stoner E, Thompson DL, Nance D, Lasseter KC. Effect of MK-906, a specific 5 alpha-reductase inhibitor, on serum androgens and androgen conjugates in normal men. J Androl. 1989 Jul-Aug;10(4):259-62.
| Storage | Store at -20°C |
| M.Wt | 432.6 |
| Cas No. | 222989-99-3 |
| Formula | C25H40N2O4 |
| Solubility | Soluble in DMSO |
| SDF | Download SDF |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
化学结构
