Bcl-2 Family
Bcl-2 family proteins are a group of proteins homologous to the Bcl-2 protein and characterized by containing at least one of four conserved Bcl-2 homology (BH) domains (BH1, BH2, BH3 and BH4). Bcl-2 family proteins, consisting of pro-apoptotic and anti-apoptotic molecules, can be classified into the following three subfamilies according to sequence homology within four BH domains: (1) a subfamily shares sequence homology within all four BH domains, such as Bcl-2, Bcl-XL and Bcl-w which are anti-apoptotic; (2) a subfamily shares sequence homology within BH1, BH2 and BH4, such as Bax and Bak which are pro-apoptotic; (3) a subfamily shares sequence homology only within BH3, such as Bik and Bid which are pro-apoptotic.
- A9902 Bcl Family Set ISummary: Bcl家族抑制剂
- A4466 Muristerone ASummary: TRAIL和hFasL诱导的凋亡抑制剂
- A4465 MIM11 CitationTarget: Mcl-1Summary: Mcl-1抑制剂
- A4463 BIM, BiotinylatedSummary: 连接有生物素部分的Bim肽片段
- A4461 Bax inhibitor peptide V5Target: BaxSummary: Bax抑制剂
- A4460 Bax inhibitor peptide P5Summary: Bax抑制剂
- A4459 Bax channel blockerSummary: Bax介导的线粒体细胞色素c释放的抑制剂
- A4447 2,3-DCPE hydrochlorideTarget: Apoptosis InducersSummary: Bcl-XL蛋白表达下调剂
- A3935 WEHI-53915 CitationTarget: Bcl-xlSummary: 选择性的Bcl-xL抑制剂
- A3424 Gambogic Acid中文名: 藤黄酸Summary: Caspase激活剂和凋亡诱导剂