Monoacetylphloroglucinol
| 规格 | 价格 | 货期 | 数量 |
|---|---|---|---|
| 1mL(10 mM in DMSO) | ¥385.00 | 现货 | |
| 10g | ¥305.00 | 现货 | |
| 25g | ¥641.00 | 现货 |
特色产品
- 用于免疫印迹和质谱分析等后续操作
- 适用于30 KDa-130 KDa大小的蛋白
- 可将信号灵敏度提高100倍
- 同时保持稳定的特异性和分辨率
- 提供更高的转录效率并抑制免疫激活
- 使用5-moUTP和Cy5-utp修饰
产品描述
Monoacetylphloroglucinol (MAPG), small molecular weight phenolic metabolite, is produced via bacteria including Pseudomonas strains. MAPG is acetylated to form the broad-spectrum antibiotic, 2,4-diacetylphloroglucinol (DAPG) by MAPG acetyltransferase. In addition, MAPG exerts fairly weak potency when exhibiting a broad range of antibiotic activity. Even though weakly active, it seems that MAPG is essential in the biocontrol of plant diseases by some Pseudomonas strains [1].
In vitro: Up to now, in vitro study of MAPG is still in the development stage.
In vivo: Up to now, in vivo study of MAPG is still in the development stage.
Reference:
[1]. HAYASHI, A., SAITOU, H., MORI, T., MATANO, I., SUGISAKI, H., & MARUYAMA, K. Molecular and Catalytic Properties of Monoacetylphloroglucinol Acetyltransferase fromPseudomonassp. YGJ3. Bioscience, Biotechnology, And Biochemistry. 2012; 76(3): 559-566.
产品性质
| 物理外观 | Solid |
| CAS号 | 480-66-0 |
| 分子式 | C8H8O4 |
| 分子量 | 168.1 |
| 小分子别名 | Phloracetophenone |
| 化学名称 | 1-(2,4,6-trihydroxyphenyl)-ethanone |
| 溶解度 | insoluble in H2O; ≥25.9 mg/mL in EtOH; ≥8.05 mg/mL in DMSO |
| SMILES | CC(c(c(O)cc(O)c1)c1O)=O |
| 存储条件 | -20°C |
| 运输条件 | 蓝冰 |
产品应用 (实验数据来自文献,APExBIO并未验证,仅供参考)
IC50和靶点
| 生物活性描述 | 氯苯乙酮(2,4,6-三羟基苯乙酮)是从莪术中提取的苯乙酮苷的苷元部分,具有降低胆固醇的活性。氯苯乙酮能增强胆固醇 7α- 羟化酶(CYP7A1)的活性。氯苯乙酮通过 Mrp2 促进胆汁分泌。 |



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