Interleukin II (60-70)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
白细胞介素II(60-70),化学式为C68H104N14O14S,氨基酸序列NH2 LEU-THR-PHE-LYS-PHE-TYR-MET-PRO-LYS-LYS-ALA-COOH,分子量为1373.7。白细胞介素-2(IL-2)是免疫系统的细胞因子信号分子,调节白细胞(淋巴细胞)的活性,对免疫应答具有重要作用。IL-2是免疫系统的可溶性激素样调节剂,是鉴定和表征的第一个白介素分子。IL-2对T细胞的生长、增殖和分化成“效应子”T细胞是必须的。IL-2是在免疫应答过程中由T细胞产生的,对于T细胞免疫记忆的发育具有重要作用,T细胞免疫记忆依赖于抗原选择性T细胞的数目和功能。成熟的T细胞又称为调节性T细胞,在胸腺T细胞的发展中,IL-2对T细胞的成熟是必须的。
Figure1 Formula of Interleukin II (60-70)
Figure2 Summary of effects of Interleukin II
参考文献:
1. Cantrell DA, Smith KA (June 1984). "The interleukin-2 T-cell system: a new cell growth model". Science 224 (4655): 1312–6.
2. Smith KA (May 1988). "Interleukin-2: inception, impact, and implications". Science 240 (4856): 1169–76.
3. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (August 1995). "Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases". J. Immunol. 155 (3): 1151–64.
4. ThorntonAM, Shevach EM (July 1998). "CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production". J. Exp. Med. 188 (2): 287–96.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 1373.7 |
Formula | C68H104N14O14S1 |
Synonyms | H2N-Leu-Thr-Phe-Lys-Phe-Tyr-Met-Pro-Lys-Lys-Ala-OH |
Solubility | insoluble in EtOH; ≥11.34 mg/mL in H2O; ≥137.3 mg/mL in DMSO |
SDF | Download SDF |
Canonical SMILES | N[C@@H](CC(C)C)C(N[C@H]([C@@H](C)O)C(N[C@H](CC1=CC=CC=C1)C(N[C@H](CCCCN)C(N[C@H](CC2=CC=CC=C2)C(N[C@H](CC3=CC=C(O)C=C3)C(N[C@H](CCSC)C(N4CCC[C@@H]4C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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