Fusion glycoprotein (92-106) [Human respiratory syncytial virus]
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
融合糖蛋白(92-106)[人类呼吸道合胞病毒]的化学式为C73H124N22O25S,氨基酸序列为H2N-Glu-Leu-Gln-Leu-Leu-Met-Gln-Ser-Thr-Pro-Pro-Thr-Asn-Asn-Arg-OH,分子量为1741.96。糖链(聚糖)与多肽侧链共价连接形成糖蛋白。在共翻译或翻译后修饰过程中,碳水化合物连接到蛋白质上,这个过程称为糖基化。分泌的胞外蛋白通常是糖基化蛋白质。在具有细胞外延伸部分的蛋白中,其胞外部分通常也被糖基化。糖蛋白往往是重要的整合膜蛋白,在细胞-细胞相互作用中发挥作用。糖蛋白也在胞质中形成,但对它们在胞质中的功能和修饰途径了解较少(1)。体内糖蛋白的例子,如粘蛋白可以分泌到呼吸道和消化道的粘液中,连接到粘蛋白的多糖具有相当大的保水能力,使它们对消化酶的蛋白酶解产生抗性。糖蛋白对白细胞识别非常重要,特别是在哺乳动物中(2)。在免疫系统中的糖蛋白,如抗体(免疫球蛋白),可与抗原直接作用。还有组织相容性复合体(或MHC),表达在细胞膜上,并与T细胞相互作用,是适应性免疫反应的一部分。
Figure1 the structures of glycoprotein
Figure 2 Mechanisms of glycoprotein cell receptors
参考文献:
1. Ruddock & Molinari (2006) Journal of Cell Science 119, 4373–4380
2. Funakoshi Y, Suzuki T (January 2009). "Glycobiology in the cytosol: The bitter side of a sweet world". Biochim. Biophys. Acta 1790 (2): 81–94.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 1741.96 |
Formula | C73H124N22O25S |
Synonyms | H2N-Glu-Leu-Gln-Leu-Leu-Met-Gln-Ser-Thr-Pro-Pro-Thr-Asn-Asn-Arg-OH |
Solubility | ≥174.2 mg/mL in DMSO; insoluble in EtOH; ≥11.46 mg/mL in H2O |
SDF | Download SDF |
Canonical SMILES | CC(CCC(C(NC(CC(C)C)C(NC(CCC(N)=O)C(NC(CC(C)C)C(NC(C(NC(CCSC)C(NC(CCC(O)=O)C(NC(CO)C(NC(C(O)C)C(N1CCCC1C(N2CCCC2C(NC(C(C)O)C(NC(CC(N)=O)C(NC(CC(N)=O)C(NC(C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC(C)C)=O)=O)=O)=O)O)=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
- 批次: