Tenofovir hydrate
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Tenofovir hydrate是一种逆转录酶抑制剂,用于治疗人类免疫缺陷病毒1型(HIV-1)和乙型肝炎.
Tenofovir hydrate是一种抗病毒前体药物,属于核苷类逆转录酶抑制剂.据报道,Tenofovir hydrate对HIV-1感染的预防功效与胞内药物浓度相关.当病毒接种量为1\5\20和100时,Tenofovir hydrate的EC50值分别为29 fmol/106\40 fmol/106\77 fmol/106和411 fmol/106(所有测定值均以106细胞为基准).而EC90值分别为267 fmol/106\348 fmol/106\640 fmol/106和2866 fmol/106[1].
参考文献：
[1] Duwal S1, Schütte C, von Kleist M. Pharmacokinetics and pharmacodynamics of the reverse transcriptase inhibitor tenofovir and prophylactic efficacy against HIV-1 infection. PLoS One. 2012;7(7):e40382. doi: 10.1371/journal.pone.0040382. Epub 2012 Jul 11.
| Storage | Store at -20°C |
| M.Wt | 305.23 |
| Cas No. | 206184-49-8 |
| Formula | C9H16N5O5P |
| Solubility | Soluble in DMSO |
| Chemical Name | [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid;hydrate |
| SDF | Download SDF |
| Canonical SMILES | CC(CN1C=NC2=C1N=CN=C2N)OCP(=O)(O)O.O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
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化学结构
