Oleic Acid
一种单不饱和脂肪酸
| 规格 | 价格 | 货期 | 数量 |
|---|---|---|---|
| 500mg | ￥153.00 | 现货 | |
| 1g | ￥189.00 | 现货 | |
| 5g | ￥614.00 | 现货 | |
| 10g | ￥768.00 | 现货 |
特色产品
- 适用于流式细胞仪和荧光显微镜检测
- 准确区分活细胞/凋亡细胞/坏死细胞
- 用于免疫印迹和质谱分析等后续操作
- 适用于30 KDa-130 KDa大小的蛋白
- 对细胞无毒性
- 步骤更简单，无需有机溶剂
- 可将信号灵敏度提高100倍
- 同时保持稳定的特异性和分辨率
- 提供更高的转录效率并抑制免疫激活
- 使用5-moUTP和Cy5-utp修饰
- 优异的扩增效率、可重复性和稳定性
- 卓越的灵敏度和准确性，操作简单
- 优化的缓冲液和T7 RNA聚合酶混合物
- 20 μL反应体系可获得更高的RNA产量
产品描述
Oleic acid is a monounsaturated fatty acid naturally found in many animal and vegetable fats and oils.
In 786-O cells, treatment with oleic acid upregulated ILK. In breast cancer, oleic acid activates G protein-coupled receptors and phosphorylates ERK1/2, inducing cancer cell proliferation[1].
Oleic acid inhibits Na/K-ATPase activity in the lungs and lungs during injury. Oleic acid (10 μM) induces pulmonary edema, inflammation and cell influx, liposome formation, and the production of leukotriene B4 (LTB4) and PGE2[2].
Reference:
[1]. Harvey K A, Walker C L, Xu Z, et al. Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. Journal of Lipid Research, 2010, 51(12): 3470-3480.
[2]. Goncalvesdealbuquerque C F, Burth P, Silva A R, et al. Oleic acid inhibits lung Na/K-ATPase in mice and induces injury with lipid body formation in leukocytes and eicosanoid production. Journal of Inflammation, 2013, 10(1): 34-34.
产品性质
| 物理外观 | A liquid |
| CAS号 | 112-80-1 |
| 分子式 | C18H34O2 |
| 分子量 | 282.46 |
| 小分子别名 | Oleic acid |
| 化学名称 | oleic acid |
| 溶解度 | insoluble in H2O; ≥58.2 mg/mL in DMSO; ≥62 mg/mL in ETOH |
| SMILES | CCCCCCCC/C=C\CCCCCCCC(O)=O |
| 存储条件 | -20°C |
| 运输条件 | 蓝冰 |
产品应用 (实验数据来自文献，APExBIO并未验证，仅供参考)
IC50和靶点
| 生物活性描述 | 油酸（9-顺式-十八烯酸）是一种丰富的单不饱和脂肪酸。油酸是一种 Na+/K+ ATP 酶激活剂。 |
| 靶点 | ATPase |
质量控制
操作说明
APExBIO 顾客使用本产品发表的 8 篇科研文献
6. Mingning Ding, Fei Zhou, et al. "Cassiae Semen improves non-alcoholic fatty liver disease through autophagy-related pathway." Chin Herb Med. 2023 Mar 22;15(3):421-429. PMID: 37538867
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