PAF (C16)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
PAF（C16）是一种内源血小板活化因子（PAF）和PAF受体的配体。
血小板活化因子受体是一种G蛋白偶联受体，可结合血小板活化因子。
PAF在炎性细胞和多形核中性粒细胞中产生。该物质可诱导血管通透性增加。为检测选择性内皮通透性下降，通过监控125I-白蛋白（6.7 nm）、125I-低密度脂蛋白（22.0 nm）和125I-极低密度脂蛋白（62.1 nm）在血浆中的下降来评估PAF的外渗效果。标记的血浆示踪物质无选择性血浆保留，表明PAF诱导的外渗具有剂量依赖性，并提高血管通透性[1]。
给雄性Wistar大鼠肾脏动脉循环施用PAF（C16）可以剂量依赖的方式提高肾脏血流（6-15%）。PAF诱导的系统性低血压和肾脏血管扩张不依赖于肾脏神经支配，而是由PAF受体介导[2]。
参考文献：
[1]. Handley DA, Arbeeny CM, Lee ML, et al. Effect of platelet activating factor on endothelial permeability to plasma macromolecules. Immunopharmacology, 1984, 8(3-4): 137-142.
[2]. Handa RK, Strandhoy JW, Buckalew VM Jr. Platelet-activating factor is a renal vasodilator in the anesthetized rat. Am J Physiol, 1990, 258(6 Pt 2): F1504-1509.
| Physical Appearance | A lyophilized powder |
| Storage | Desiccate at -20°C |
| M.Wt | 523.68 |
| Cas No. | 74389-68-7 |
| Formula | C26H54NO7P |
| Solubility | Soluble in H2O or ethanol |
| Chemical Name | (R)-2-acetoxy-3-(hexadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate |
| SDF | Download SDF |
| Canonical SMILES | [O-][P@@](OCC[N+](C)(C)C)(OC[C@@H](COCCCCCCCCCCCCCCCC)OC(C)=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
化学结构
