Orexin A (human, rat, mouse)
| 规格 | 价格 | 货期 | 数量 |
|---|---|---|---|
| 500ug | ￥2612.00 | 现货 | |
| 1mg | ￥4180.00 | 现货 | |
| 5mg | ￥15048.00 | 现货 |
特色产品
- 适用于流式细胞仪和荧光显微镜检测
- 准确区分活细胞/凋亡细胞/坏死细胞
- 用于免疫印迹和质谱分析等后续操作
- 适用于30 KDa-130 KDa大小的蛋白
- 对细胞无毒性
- 步骤更简单，无需有机溶剂
- 可将信号灵敏度提高100倍
- 同时保持稳定的特异性和分辨率
- 提供更高的转录效率并抑制免疫激活
- 使用5-moUTP和Cy5-utp修饰
- 优异的扩增效率、可重复性和稳定性
- 卓越的灵敏度和准确性，操作简单
- 优化的缓冲液和T7 RNA聚合酶混合物
- 20 μL反应体系可获得更高的RNA产量
产品描述
Orexin A, a 33 amino acid hypothalamic neuropeptide, is an endogenous agonist at orexin-1 and -2 receptors[1]. It play a role in appetite regulation, wakefulness, locomotor activity, hypothalamic-pituitary-adrenal activity, and pain thresholds[2].
Orexin A (10 and 30 mg/kg i.v., 5 min pre-plantar test) increases the latency to thermally stimulated paw contraction to baseline levels. Orexin A (3-30 mg/kg; i.v.; 5 min pre-test) significantly increases the reaction latency of intravenous reactions of 10 and 30 mg/kg[3].
References:
[1]. Rodgers R J, Ishii Y, Halford J C G, et al. Orexins and appetite regulation. Neuropeptides, 2002, 36(5): 303-325 .
[2]. Lang M, Söll R M, Dürrenberger F, et al. Structure-activity studies of orexin A and orexin B at the human orexin 1 and orexin 2 receptors led to orexin 2 receptor selective and orexin 1 receptor preferring ligands. Journal of Medicinal Chemistry, 2004, 47(5): 1153-1160.
[3]. Bingham S, et al. Orexin-A, an hypothalamic peptide with analgesic properties. Pain, 2001, 92(1-2): 81-90.
产品性质
| 物理外观 | A crystalline solid |
| CAS号 | 205640-90-0 |
| 分子式 | C152H247N47O44S4 |
| 分子量 | 3565.14 |
| 溶解度 | ≥50.4 mg/mL in DMSO; ≥12.4 mg/mL in EtOH with ultrasonic; ≥50.7 mg/mL in H2O |
| SMILES | CC[C@]([C@@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O)/[C@](/N=C(O) |
| 存储条件 | -20°C干燥 |
| 运输条件 | 蓝冰 |
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