Moxalactam (sodium salt)
| 规格 | 价格 | 货期 | 数量 |
|---|---|---|---|
| 1mL(10 mM in DMSO) | ￥454.00 | 现货 | |
| 250mg | ￥400.00 | 现货 | |
| 500mg | ￥609.00 | 现货 | |
| 1g | ￥1018.00 | 现货 |
特色产品
- 适用于流式细胞仪和荧光显微镜检测
- 准确区分活细胞/凋亡细胞/坏死细胞
- 用于免疫印迹和质谱分析等后续操作
- 适用于30 KDa-130 KDa大小的蛋白
- 对细胞无毒性
- 步骤更简单，无需有机溶剂
- 可将信号灵敏度提高100倍
- 同时保持稳定的特异性和分辨率
- 提供更高的转录效率并抑制免疫激活
- 使用5-moUTP和Cy5-utp修饰
- 优异的扩增效率、可重复性和稳定性
- 卓越的灵敏度和准确性，操作简单
- 优化的缓冲液和T7 RNA聚合酶混合物
- 20 μL反应体系可获得更高的RNA产量
产品描述
Moxalactam (sodium salt) is a β-lactam antibiotic.
β-lactam antibiotics (beta-lactam antibiotics) are a class of broad-spectrum antibiotics that contain a beta-lactam ring in their molecular structures. Most β-lactam antibiotics act by inhibiting cell wall biosynthesis.
Moxalactam is an oxacephem antibiotic and inhibits most commonly occurring gram positive, gram negative, and anaerobic bacteria. Moxalactam was more active against Klebsiella and E coli than cefoperazone. Moxalactam did not inhibit methicillin-resistant S. aureus and Enterococci. Moxalactam had been extremely active against Haemophilis and Neisseria gonorrhoeae. Moxalactam was extremely resistant to hydrolysis by all plasmid and chromosmal β-lactamases [1]. In certain situations, Moxalactam impaired normal hemostasis and prolonged bleeding time [2].
References:
[1]. Neu HC. The in vitro activity, human pharmacology, and clinical effectiveness of new beta-lactam antibiotics. Annu Rev Pharmacol Toxicol. 1982;22:599-642.
[2]. Sattler FR, Weitekamp MR, Ballard JO. Potential for bleeding with the new beta-lactam antibiotics. Ann Intern Med. 1986 Dec;105(6):924-31.
产品性质
| 物理外观 | Solid |
| CAS号 | 64953-12-4 |
| 分子式 | C20H18N6O9S·2Na |
| 分子量 | 564.4 |
| 小分子别名 | Moxalactam sodium salt |
| 化学名称 | (6R,7R)-7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, disodium salt |
| 溶解度 | ≥25.95 mg/mL in DMSO; insoluble in EtOH; ≥62.6 mg/mL in H2O |
| SMILES | OC1=CC=C([C@@H](C([O-])=O)C(N[C@@]2(OC)[C@](OCC(CSC3=NN=NN3C)=C4C([O-])=O)([H])N4C2=O)=O)C=C1.[Na+].[Na+] |
| 存储条件 | -20°C |
| 运输条件 | 蓝冰 |
产品应用 (实验数据来自文献，APExBIO并未验证，仅供参考)
IC50和靶点
| 生物活性描述 | 莫沙内酰胺（Latamoxef）钠盐是一种合成的氧杂-β-内酰胺类抗生素。莫沙内酰胺钠盐对革兰氏阳性和革兰氏阴性需氧和厌氧菌具有广谱活性。莫沙内坦钠盐可抑制 β-内酰胺酶的产生。 |
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