MK-4827 tosylate
尼拉帕尼甲苯磺酸盐
Catalog No.
B1164
PARP1/PARP2抑制剂
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MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 492.59 |
| Cas No. | 1038915-73-9 |
| Formula | C26H28N4O4S |
| Solubility | Soluble in DMSO |
| Chemical Name | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carbimidic acid compound with 4-methylbenzenesulfonic acid (1:1) |
| SDF | Download SDF |
| Canonical SMILES | N=C(O)C1=CC=CC(C1=N2)=CN2C3=CC=C([C@]4([H])CCCNC4)C=C3.CC5=CC=C(S(O)(=O)=O)C=C5 |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
化学结构
