KKL10
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
KKL-10是一种具有广谱抗菌活性的小分子核糖体拯救抑制剂。核糖体拯救抑制剂KKL-10对F. Tularensis的减毒和全毒株均表现出卓越的抗菌活性。对F. tularensis LVS和Schu S4的最小抑制浓度(MIC)分别为0.12和0.48 μg/mL。在感染的所有阶段，KKL-10都会阻止F. tularensis的细胞内生长。KKL-10不影响巨噬细胞活力或功能。KKL-10在浓度高达17.5 μg/mL时产生不到5%的细胞毒作用[1]。
参考文献：
[1]. Goralski TD, Dewan KK, Alumasa JN, Avanzato V, Place DE, Markley RL, Katkere B, Rabadi SM, Bakshi CS, Keiler KC, Kirimanjeswara GS. Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication. Antimicrob Agents Chemother. 2016 May 23;60(6):3276-82. doi: 10.1128/AAC.03089-15. PMID: 26953190; PMCID: PMC4879415.
| Storage | Store at -20°C |
| M.Wt | 364.22 |
| Cas No. | 952849-76-2 |
| Formula | C14H10BrN3O2S |
| Solubility | ≥4.7 mg/mL in DMSO with ultrasonic |
| Chemical Name | 5-bromo-N-(5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thiophene-2-carboxamide |
| SDF | Download SDF |
| Canonical SMILES | O=C(C1=CC=C(Br)S1)NC2=NN=C(C3=CC=C(C)C=C3)O2 |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
