Famciclovir
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Famciclovir是喷昔洛韦的口服前药[1].
Famciclovir是抗疱疹病毒药物喷昔洛韦的口服前药,而喷昔洛韦在啮齿动物中口服给药时很难吸收.Famciclovir是6-脱氧喷昔洛韦的二酯衍生物.在大鼠组织和体液以及人类组织和体液中,该物质可被迅速吸收并转化为有效的抗病毒药.除此之外,famciclovir在十二指肠腔中相对稳定,可维持稳定的血液喷昔洛韦水平.目前,famciclovir被批准用于免疫功能完全的成年病人的带状疱疹\唇疱疹\生殖器疱疹以及免疫功能不全的成人的HSV的治疗[1,2].
参考文献：
[1] Hodge R A V, Sutton D, Boyd M R, et al. Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl) guanine; penciclovir]. Antimicrobial agents and chemotherapy, 1989, 33(10): 1765-1773.
[2] Sáez-Llorens X, Yogev R, Arguedas A, et al. Pharmacokinetics and safety of famciclovir in children with herpes simplex or varicella-zoster virus infection. Antimicrobial agents and chemotherapy, 2009, 53(5): 1912-1920.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 321.33 |
| Cas No. | 104227-87-4 |
| Formula | C14H19N5O4 |
| Solubility | ≥17.83 mg/mL in H2O with ultrasonic; ≥32.7 mg/mL in EtOH; ≥8.8 mg/mL in DMSO |
| Chemical Name | [2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate |
| SDF | Download SDF |
| Canonical SMILES | CC(=O)OCC(CCN1C=NC2=CN=C(N=C21)N)COC(=O)C |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
