Entecavir Hydrate
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Entecavir hydrate是一种逆转录酶抑制剂。
逆转录酶（RT）可以RNA为模板合成互补DNA（cDNA），主要与逆转录病毒如HBV有关。
Entecavir hydrate是一种用于治疗乙肝病毒（HBV）感染的口服抗病毒药。在对17个携带乙肝病毒（HBV）基因型C患者的实验中，使用聚乙二醇干扰素（PEG-IFN）a-2b结合entecavir hydrate（ETV）治疗48周。其中11个病人展示出治疗前HBeAg，8个有HBeAg血清转化。血浆HBV的DNA水平在治疗结束和随访期间分别下降了5.2和3.3 log拷贝/ml。肝内cccDNA下降到1.4 log拷贝/mg。
参考文献：
[1]. Hagiwara S, Kudo M, Osaki Y, et al. Impact of peginterferon alpha-2b and entecavir hydrate combination therapy on persistent viral suppression in patients with chronic hepatitis B. J Med Virol, 2013, 85(6): 987-995.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 295.29 |
| Cas No. | 209216-23-9 |
| Formula | C12H15N5O3·H2O |
| Solubility | insoluble in EtOH; insoluble in H2O; ≥9.7 mg/mL in DMSO |
| Chemical Name | 2-amino-9-[(3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-3H-purin-6-one;hydrate |
| SDF | Download SDF |
| Canonical SMILES | C=C1C(CC(C1CO)O)N2C=NC3=C2NC(=NC3=O)N.O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
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化学结构
