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Cercosporamide

尾孢素酰胺
Catalog No.
A4511
Mnk2和JAK3抑制剂
组合的产品项目
规格价格库存 数量
500ug
¥ 5,890.00
Ship with 10-15 days
1mg
¥ 9,763.00
Ship with 10-15 days

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A

背景

Potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) and JAK3 (IC50 values are 11, 31 and 116 nM for Mnk2, JAK3 and Mnk1 respectively). Blocks eIF4E phosphorylation; exhibits antiproliferative and proapoptotic activity in cancer cells in vitro. Also inhibits Pkc1. Orally bioavailable.

化学属性

Physical AppearanceA light to dark tan solid
StorageStore at -20°C
M.Wt331.28
Cas No.131436-22-1
FormulaC16H13NO7
SolubilityLimited solubility, soluble in DMSO
Chemical Name(9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxodibenzofuran-4-carboxamide
SDFDownload SDF
Canonical SMILESCC(=O)C1=C(C=C2C(C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O
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质量控制

质量控制和MSDS

批次:

化学结构

Cercosporamide