Ceftazidime
| 规格 | 价格 | 货期 | 数量 |
|---|---|---|---|
| 1g | ￥563.00 | 现货 | |
| 5g | ￥1036.00 | 现货 |
特色产品
- 适用于流式细胞仪和荧光显微镜检测
- 准确区分活细胞/凋亡细胞/坏死细胞
- 用于免疫印迹和质谱分析等后续操作
- 适用于30 KDa-130 KDa大小的蛋白
- 对细胞无毒性
- 步骤更简单，无需有机溶剂
- 可将信号灵敏度提高100倍
- 同时保持稳定的特异性和分辨率
- 提供更高的转录效率并抑制免疫激活
- 使用5-moUTP和Cy5-utp修饰
- 优异的扩增效率、可重复性和稳定性
- 卓越的灵敏度和准确性，操作简单
- 优化的缓冲液和T7 RNA聚合酶混合物
- 20 μL反应体系可获得更高的RNA产量
产品描述
Ceftazidime is categorized as a third-generation cephalosporin which show a broad spectrum of in vitro activity against both Gram-positive and Gram-negative aerobic bacteria, including Pseudomonas aeruginosa (P. aeruginosa). In fact, ceftazidime is by far the most active cephalosporin available against P. aeruginosa in vitro, but it is less active against Staphylococcus aureus (S. aureus) than first and second generation cephalosporins. Also, ceftazidime is particularly active against most Enterobacteriaceae, including β-lactamase-positive strains, since it is highly resistant to hydrolysis induced by β-Iactamases.
Reference:
1. Richards DM, Brogden RN. Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs, 1985, 29(2): 105-161.
产品性质
| 物理外观 | A solid |
| CAS号 | 72558-82-8 |
| 分子式 | C22H22N6O7S2 |
| 分子量 | 546.58 |
| 化学名称 | 2-(((Z)-((Z)-2-(((6R,7R)-2-carboxy-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)imino)-2-hydroxy-1-(2-imino-2,3-dihydrothiazol-4-yl)ethylidene)amino)oxy)-2-methylpropanoate |
| 溶解度 | ≥21.25 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
| SMILES | O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N\OC(C)(C(O)=O)C)=O)[C@@]3([H])SCC(C[N+]4=CC=CC=C4)=C(C([O-])=O)N13 |
| 存储条件 | -20°C |
| 运输条件 | 蓝冰 |
产品应用 (实验数据来自文献，APExBIO并未验证，仅供参考)
IC50和靶点
| 生物活性描述 | 头孢他啶（Ceftazidime，GR20263）是一种抗生素，对革兰阳性和革兰阴性需氧菌具有广谱活性。头孢他啶对肠杆菌科细菌（包括β-内酰胺酶阳性菌株）也有活性，并能抵抗大多数β-内酰胺酶的水解作用。 |
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