Calcium Ionophore I
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Calcium Ionophore I，也称作CA 1001或ETH 1001，是一种Ca2+选择性的离子载体[1][2]。
离子载体可以选择性的改变膜的离子通透性，从而模拟生物膜中正常离子载体的特性，可用于研究膜的功能[2]。
Calcium Ionophore I是一种Ca2+选择性的中性载体。在源自人RBCs的负载Ca2 +的IOVs中，ETH 1001促进Ca2+流穿过RBC膜。ETH 1001处理的细胞中Ca2+的数量显著高于对照细胞。在外部Ca2 +存在下，ETH 1001能够运输Ca2+进入RBCs [3]。CA 1001也用于构建Ca2+选择性的膜微电极[4][5]。
参考文献：
Dagostino M, Lee CO. Neutral carrier Na+- and Ca2+-selective microelectrodes for intracellular application. Biophys J. 1982 Dec;40(3):199-207.
Caroni P, Gazzotti P, Vuilleumier P, et al. Ca2+ transport mediated by a synthetic neutral Ca2+ -ionophore in biological membranes. Biochim Biophys Acta. 1977 Nov 1;470(3):437-45.
Hinds TR, Vincenzi FF. The effect of ETH 1001 on ion fluxes across red blood cell membranes. Cell Calcium. 1985 Jun;6(3):265-79.
Lücke A, Lehmenkühler A, Speckmann EJ. The influence of the convulsant pentylenetetrazol on Ca2+-selective microelectrodes (neutral carrier ETH 1001). J Neurosci Methods. 1989 Aug;29(2):139-42.
Lee MH, Yoo CL, Lee JS, et al. Tweezer-type neutral carrier-based calcium-selective membrane electrode with drastically reduced anionic interference. Anal Chem. 2002 Jun 1;74(11):2603-7.
| Physical Appearance | A solution in ethanol |
| Storage | Store at -20°C |
| M.Wt | 684.99 |
| Cas No. | 58801-34-6 |
| Formula | C38H72N2O8 |
| Solubility | Soluble in DMSO |
| Chemical Name | (17R,18R)-diethyl 13,17,18,22-tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontane-1,34-dioate |
| SDF | Download SDF |
| Canonical SMILES | C[C@H]([C@H](OCC(N(CCCCCCCCCCCC(OCC)=O)C)=O)C)OCC(N(C)CCCCCCCCCCCC(OCC)=O)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
化学结构
