Angiotensin 1/2 (1-5)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
血管紧张素I / II（1-5）多肽序列为ASP-ARG-VAL-Tyr-Ile，是由血管紧张素I / II转化而来的，包含氨基酸1-5。
肾素作用于血管紧张素原形成血管紧张素I，血管紧张素原是一个含12个氨基酸的α2-球蛋白。血管紧张素原主要在肝脏中产生，释放到循环系统中。肾素作用于血管紧张素原的亮氨酸和缬氨酸之间的肽键，生成含有10个氨基酸的血管紧张素I，血管紧张素I在肺中血管紧张素转换酶（ACE）的作用下，除去两个C-末端残基转变为血管紧张素II（AII）。
血管紧张素是一种肽类激素，引起血管收缩及随后血压升高。也可以刺激醛固酮的释放，从而促进远端肾单位的钠滞留，增加血压。
Figure1 Formula of Angiotensin I/II (1-5)
参考文献：
1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9.
2. Richard A. Preston. et. (1998). “Age-Race Subgroup Compared With Renin Profile as Predictors of Blood Pressure Response to Antihypertensive Therapy”. JAMA. 1998;280(13):1168-1172.
3. Williams GH, Dluhy RG (2008). "Chapter 336: Disorders of the Adrenal Cortex". In Loscalzo J, Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL. Harrison's principles of internal medicine. McGraw-Hill Medical.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 664.75 |
| Cas No. | 58442-64-1 |
| Formula | C30H48N8O9 |
| Synonyms | H2N-Asp-Arg-Val-Tyr-Ile-OH |
| Solubility | insoluble in H2O; ≥66.5 mg/mL in DMSO; ≥69.5 mg/mL in EtOH |
| Chemical Name | (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoic acid |
| SDF | Download SDF |
| Canonical SMILES | CCC(C)C(C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
