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Tenovin-3

Catalog No.
A8567
p53激活剂
组合的产品项目
规格价格库存 数量
10mM (in 1mL DMSO)
¥ 1,300.00
现货
1mg
¥ 950.00
现货
5mg
¥ 1,940.00
现货
10mg
¥ 2,950.00
现货
25mg
¥ 6,270.00
现货

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Background

Tenovin SAR Studies Aimed at Increasing Water Solubility

ID
p53 Increasea K40Ac Tubulin Increaseb SirT2 Inhibitionc
R1 R2
Tenovin-1 tBu NHCOCH3 + + +
Tenovin-2 tBu NHCOCH(CH3)2 + + +
Tenovin-3 tBu NH2 + + +
Tenovin-4 N3 NHCOCH3
Tenovin-5 tBu NHCOPh + + +
Tenovin-6 tBu NHCO(CH2)4NMe2.HCl + + +
a     Ability to increase p53 levels was determined in MCF-7 cells treated for 6 hr at 10 μM.
b     Ability to increase K40 Ac-tubulin levels was determined in H1299 cells treated
c     SirT2 inhibition assessed using a compound concentration of 10 or 30 μM depending on the compound's solubility in the assay buffer.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt327.44
Cas No.1011301-27-1
FormulaC18H21N3OS
SynonymsTenovin 3;Tenovin3
Solubility≥14.45mg/mL in DMSO
Chemical NameN-[(4-aminophenyl)carbamothioyl]-4-tert-butylbenzamide
SDFDownload SDF
Canonical SMILESCC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)N
运输条件试用装:蓝冰运输。 其他可选规格:常温运输或根据您的要求用蓝冰运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。

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