RCGD423
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
RCGD423是一种糖蛋白130调节剂，可防止关节软骨退化并促进修复。通过评估与化合物孵育后健康和骨关节炎关节软骨细胞中RUNX2和COL10的水平，证实了RCGD423抑制人类细胞肥大的能力。RCGD423显着降低了软骨细胞的肥大、丢失和变性，促进了软骨细胞的增殖，超过了大鼠半月板部分切除模型中观察到的损伤反应。
参考文献：
[1]. Shkhyan R, et al. Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair. Ann Rheum Dis. 2018 May, 77(5): 760-769. PMID: 29436471
| Storage | Store at -20°C |
| M.Wt | 331.23 |
| Cas No. | 108237-91-8 |
| Formula | C15H11BrN2S |
| Solubility | ≥34.6 mg/mL in DMSO |
| Chemical Name | N-(4-bromophenyl)-4-phenylthiazol-2-amine |
| SDF | Download SDF |
| Canonical SMILES | BrC1=CC=C(C=C1)NC2=NC(C3=CC=CC=C3)=CS2 |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
