mTOR inhibitor-1
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
mTOR inhibitor-1是一种新型的mTOR通路抑制剂,它可以抑制细胞增殖并诱导自噬。mTOR inhibitor-1以时间和剂量依赖性方式抑制A549 细胞的增殖,在24小时的IC50为3.176 μM[1]。
参考文献:
[1]. Liu J, et al. In Silico Discovery of a Small Molecule Suppressing Lung Carcinoma A549 Cells Proliferation and Inducing Autophagy via mTOR Pathway Inhibition. Mol Pharm. 2018 Nov 5;15(11):5427-5436.
Storage | Store at -20°C |
M.Wt | 363.21 |
Cas No. | 468747-17-3 |
Formula | C16H15BrN2O3 |
Solubility | ≥41.9 mg/mL in DMSO |
Chemical Name | (E)-3-bromo-N'-(1-(2,4-dihydroxyphenyl)ethylidene)-4-methylbenzohydrazide |
SDF | Download SDF |
Canonical SMILES | O=C(C1=CC=C(C(Br)=C1)C)N/N=C(C)/C2=CC=C(C=C2O)O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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