Mavacoxib
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Mavacoxib 是一种新型的非甾体抗炎药 (NSAID)，也是一种有效的选择性环氧合酶-2 (COX-2) 抑制剂。 环氧合酶（COX）是花生四烯酸合成前列腺素的关键酶。据报道，COX-2在与炎症和各种癌症相关的疾病中过度表达。Mavacoxib 被批准用于治疗犬的骨关节炎。 它还对一组人和犬骨肉瘤、乳腺癌和膀胱癌细胞系具有细胞毒性。 它可以诱导细胞凋亡并抑制这些细胞的迁移。
1. Hurst EA, et al. The selective cyclooxygenase-2 inhibitor mavacoxib (Trocoxil) exerts anti-tumour effects in vitro independent of cyclooxygenase-2 expression levels. Vet Comp Oncol. 2019 Jun;17(2):194-207.
| Storage | Store at -20°C |
| M.Wt | 385.34 |
| Cas No. | 170569-88-7 |
| Formula | C16H11F4N3O2S |
| Solubility | ≥40.9 mg/mL in DMSO |
| Chemical Name | 4-(5-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide |
| SDF | Download SDF |
| Canonical SMILES | O=S(C1=CC=C(N2N=C(C=C2C3=CC=C(F)C=C3)C(F)(F)F)C=C1)(N)=O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
