matrix protein (3-15) [Zaire ebolavirus]
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Matrix protein(3-15) 是一种结构蛋白肽,连接扎伊尔埃博拉病毒的核心与病毒包膜。
埃博拉病毒(EBOV)属于单股负链RNA病毒目丝状病毒家族的成员。是人类和非人灵长类动物中严重出血热的病原体,该病具有高病死率。
基质蛋白(matrix proteins)在病毒基因组复制和转录的调控中的作用,在一些负链RNA病毒中已经明了。最近的研究表明,EBOV、VP40和VP24的基质蛋白能够抑制病毒基因组的复制和转录。
Figure 1: Ribbon image of matrix protein VP40 of theZaire ebolavirus
参考文献:
1. Hoenen T, Jung S, Herwig A, Groseth A, Becker S (2010) Both matrix proteins of Ebola virus contribute to the regulation of viral genome replication and transcription. Virology 403: 56–66.
2. Dessen A, Viktor V, Dolnik O, Klenk H, Weissenhorn W. Crystal structure of the matrix protein VP 40 from Ebola virus. The EMBO Journal (2010) 19, 4228-4236.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 1515.77 |
Formula | C69H110N16O20S |
Synonyms | H2N-Arg-Val-Ile-Leu-Pro-Thr-Ala-Pro-Pro-Glu-Tyr-Met-Glu-OH |
Solubility | ≥151.6 mg/mL in DMSO; insoluble in EtOH; ≥23.37 mg/mL in H2O |
SDF | Download SDF |
Canonical SMILES | NC(CCCNC(N)=N)C(NC(C(C)C)C(NC(C(C)CC)C(NC(CC(C)C)C(N(CCC1)C1C(NC(C(C)O)C(NC(C)C(N2CCCC2C(N3CCCC3C(NC(C(NC(CC4=CC=C(O)C=C4)C(NC(CCSC)C(NC(CCC(O)=O)C(O)=O)=O)=O)=O)CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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