JWH 133
| 规格 | 价格 | 货期 | 数量 |
|---|---|---|---|
| 1mg(solution) | ￥1225.00 | 10-15工作日发货 | |
| 5mg(solution) | ￥3674.00 | 10-15工作日发货 | |
| 10mg(solution) | ￥5320.00 | 10-15工作日发货 | |
| 25mg(solution) | ￥10566.00 | 10-15工作日发货 |
特色产品
- 适用于流式细胞仪和荧光显微镜检测
- 准确区分活细胞/凋亡细胞/坏死细胞
- 用于免疫印迹和质谱分析等后续操作
- 适用于30 KDa-130 KDa大小的蛋白
- 对细胞无毒性
- 步骤更简单，无需有机溶剂
- 可将信号灵敏度提高100倍
- 同时保持稳定的特异性和分辨率
- 提供更高的转录效率并抑制免疫激活
- 使用5-moUTP和Cy5-utp修饰
- 优异的扩增效率、可重复性和稳定性
- 卓越的灵敏度和准确性，操作简单
- 优化的缓冲液和T7 RNA聚合酶混合物
- 20 μL反应体系可获得更高的RNA产量
产品描述
JWH 133 is a synthetic cannabinoid (CB) with Ki values of 3.4 nM and 677 nM for the peripheral CB2 receptor and central CB1 receptor, respectively[1].
JWH 133 inhibits tumor growth in mice, promoting apoptosis and destroying angiogenesis[2]. JWH 133 also inhibits inflammation of experimental colitis and pancreatitis in mice and in vitro models[3].
References：
[1]. Huffman J W, Liddle J, Yu S, et al. 3-(1',1'-Dimethylbutyl)-1-deoxy-Δ8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry, 1999, 7: 2905-2914.
[2]. Casanova M L, Blázquez C, Martínez-Palacio J, et al. Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors. Journal of Clinical Investigation, 2003, 111(1): 43-50.
[3]. Kimball E S, Schneider C R, Wallace N H, et al. Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium. American Journal of Physiology and Gastrointestinal Liver Physiology, 2006, 291(2): G364-G371.
产品性质
| 物理外观 | A solution in methyl acetate. To change the solvent, simply evaporate the acetate containing under a gentle stream of nitrogen and immediately add the solvent of choice. |
| CAS号 | 259869-55-1 |
| 分子式 | C22H32O |
| 分子量 | 312.49 |
| 化学名称 | (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene |
| 溶解度 | Soluble in DMSO |
| SMILES | CCCC(C)(C)c1cc(OC(C)(C)[C@H]2[C@H]3CC(C)=CC2)c3cc1 |
| 存储条件 | -20°C |
| 运输条件 | 蓝冰 |
沪公网安备 31011002003500