HBcAg [Hepatitis B virus] (18-27)
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
HBcAg（核心抗原）是乙型肝炎病毒蛋白(1)(2)。它是病毒复制活跃的指示剂，这意味着感染乙型肝炎的人可以很容易将病毒传播给另一个人。HBeAg是乙肝表面抗原（HBcAg）的细胞外形式，两者都是病毒复制的标记物，针对这些抗原的抗体是复制下降的标志。相同的DNA序列可产生多种蛋白产品。当“ORF Core”和“Pre C”共同翻译，产生“HBeAg”。而HBcAg被认为是“颗粒”，“HBeAg”被认为是“非颗粒”或“分泌”。HBeAg和HBcAg来源于相同的阅读框，HBeAg从细胞中分泌，在血清中累积，作为免疫学上不同的可溶性抗原。HBeAg分泌并在患者的血清中发现，可作为慢性肝炎中复制活跃的标记。虽然HBeAg的功能尚不完全清楚，有研究表明，它下调肝细胞和单核细胞中Toll样受体2的表达，导致细胞因子表达的减少。HBeAg对于复制是可有可无的，pre-C区缺陷的突变病毒仍具有感染性和致病性(3)。
Figure1 Formula of HBcAg [Hepatitis B virus] (18-27)
Figure 2 the HBV particle and surface antigen
参考文献：
1. Kimura T, Rokuhara A, Matsumoto A, et al. (May 2003). "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA". J. Clin. Microbiol. 41 (5): 1901–6.
2. Cao T, Meuleman P, Desombere I, Sällberg M, Leroux-Roels G (December 2001). "In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type T-cell clones in a hu-PBL-NOD/SCID mouse model". J. Virol. 75 (23): 11449–56.
3. Mandell,Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. page 2062
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 1155.3 |
| Formula | C58H78N10O15 |
| Synonyms | H-Phe-Leu-Pro-Ser-Asp-Phe-Phe-Pro-Ser-Val-OH |
| Solubility | ≥115.5 mg/mL in DMSO; ≥44.3 mg/mL in EtOH; ≥8.2 mg/mL in H2O |
| SDF | Download SDF |
| Canonical SMILES | N[C@H](C(N[C@H](C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=CC=C3)C(N4[C@@H](CCC4)C(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)CO)=O)=O)=O)=O)CC(O)=O)=O)=O)=O)CC(C)C)=O)CC5=CC=CC=C5 |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
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