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GSK2881078

Catalog No.
C4768
选择性雄激素受体调节剂(SARM)
组合的产品项目
规格价格库存 数量
5mg
¥ 2,422.00
Ship with 10-15 days
10mg
¥ 4,284.00
Ship with 10-15 days
25mg
¥ 9,394.00
Ship with 10-15 days

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Background

GSK2881078 is a potent and selective androgen receptor modulator (SARM) [1].

Steroidal nuclear receptor (NR) ligands play important roles in the health of both men and women. Dihydrotestosterone (DHT) and testosterone (T) are endogenous steroidal ligands for the androgen receptor (AR) that play a role in every tissue type found in the mammalian body. During the development of the fetus, androgens play an important role in sexual differentiation and development of male sexual organs. SARMs are small molecule pharmacotherapeutics that have the potential to afford the important benefits of androgen therapy without the undesired side-effects [1].

GSK2881078 is a potent and selective androgen receptor modulator (SARM) that is being evaluated for effects on muscle growth and strength in subjects with muscle wasting to improve their physical function. GSK2881078 is currently in phase I clinical trials [1].

Reference:
[1].  https://newdrugapprovals.org/2016/06/14/gsk-2881078/

Chemical Properties

Physical AppearanceA crystalline solid
StorageStore at -20°C
M.Wt330.3
Cas No.1539314-06-1
FormulaC14H13F3N2O2S
Solubility≤20mg/ml in ethanol;25mg/ml in DMSO;25mg/ml in dimethyl formamide
Chemical Name1-[(1R)-1-methyl-2-(methylsulfonyl)ethyl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile
SDFDownload SDF
Canonical SMILESCS(C[C@@H](C)N1C2=CC=C(C#N)C(C(F)(F)F)=C2C=C1)(=O)=O
运输条件试用装:蓝冰运输。 其他可选规格:常温运输或根据您的要求用蓝冰运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。

质量控制

质量控制和MSDS

批次:

化学结构

GSK2881078