CAY10465
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
CAY 10465是一种选择性的，高亲和性的芳香烃受体(AhR)激动剂，Ki值为0.2 nM，对雌激素受体(estrogen receptor)无作用(Ki>100000 nM)[1]。CAY 10465 (0.01 nM-100 μM)降低HepG2细胞中的载脂蛋白A-I(apo A-I)水平，并抑制蛋白质的合成[2]。
参考文献：
[1]. de Medina P, Casper R, Savouret JF, Poirot M. Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. J Med Chem. 2005 Jan 13;48(1):287-91. doi: 10.1021/jm0498194. PMID: 15634023.
[2]. Naem E, Alcalde R, Gladysz M, Mesliniene S, Jaimungal S, Sheikh-Ali M, Haas MJ, Wong NC, Mooradian AD. Inhibition of apolipoprotein A-I gene by the aryl hydrocarbon receptor: a potential mechanism for smoking-associated hypoalphalipoproteinemia. Life Sci. 2012 Jul 26;91(1-2):64-9. doi: 10.1016/j.lfs.2012.06.002. Epub 2012 Jun 19. PMID: 22727790.
| Storage | Store at -20°C |
| M.Wt | 317.13 |
| Cas No. | 688348-33-6 |
| Formula | C15H9Cl2F3 |
| Solubility | ≥32.4 mg/mL in DMSO |
| Chemical Name | (E)-1,3-dichloro-5-(4-(trifluoromethyl)styryl)benzene |
| SDF | Download SDF |
| Canonical SMILES | FC(C1=CC=C(/C=C/C2=CC(Cl)=CC(Cl)=C2)C=C1)(F)F |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 不同厂家不同批次产品溶解度各有差异，仅做参考。若实验所需浓度过大至产品溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
质量控制和MSDS
- 批次:
化学结构
