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[Ala107]-MBP (104-118)

Catalog No.
B5218
PKC抑制剂
组合的产品项目
规格价格库存 数量
1mg
¥ 4,100.00
Ship with 10-15 days

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Background

[Ala107]-MBP (104-118) is a non-competitive inhibitor of PKC and synthetic peptide analog of bovine myelin basic protein (MBP) with IC50 value of 46 - 145 mM.

References:

1. Substrate specificity of phospholipid/Ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. Turner et al. J.Biol.Chem., 1985;260:11503

2. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Su et al. Biochem.Biophys.Res.Commun., 1986;134:78

Chemical Properties

Physical AppearanceWhite lyophilised solid
StorageDesiccate at -20°C
M.Wt1493.68
Cas No.99026-77-4
SequenceGKGAGLSLSRFSWGA
FormulaC67H104N20O19
SolubilitySoluble to 1 mg/ml in 10% acetonitrile
Chemical Name(2S,3Z,6Z,8S,9Z,11S,12Z,14S,15Z,17S,18Z,20S,21Z,23S,24Z,26S,27Z,29S,30Z,33Z,35S,36Z,39Z,41S,42Z)-8-((1H-indol-3-yl)methyl)-44-amino-41-(4-aminobutyl)-14-benzyl-17-(3-guanidinopropyl)-4,7,10,13,16,19,22,25,28,31,34,37,40,43-tetradecahydroxy-11,20,26-tris(h
SDFDownload SDF
Canonical SMILESCC(C[C@@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/C/N=C(O)/[C@](/N=C(O)/CN)([H])CCCCN)([H])C)([H])/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/C/C(O)=N/[C@@](C(O)=O)([H])C)([H])CC1=CNC2=CC=CC=C12)([H])CO)
运输条件试用装:蓝冰运输。 其他可选规格:常温运输或根据您的要求用蓝冰运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。