surface antigen (208-215) [Hepatitis B Virus]
mRNA synthesis
In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
Tyramide Signal Amplification (TSA)
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Phos Binding Reagent Acrylamide
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
Cell Counting Kit-8 (CCK-8)
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
SYBR Safe DNA Gel Stain
Safe and sensitive stain for visualization of DNA or RNA in agarose or acrylamide gels.
Inhibitor Cocktails
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
乙型肝炎病毒的核衣壳由HBV表面抗原(HBsAg)的外壳蛋白包裹,其具有共同的、属特异性的抗原决定簇a。HBsAg具有四个主要亚型,即adw、ADR、ayw和ayr,他们代表了HBV四个主要基因型的表型表达1。乙肝表面抗原(HBsAg)亚型具有不同的地域分布2,可为携带特定亚型的原始乙肝病毒的迁移提供历史信息3。
HBsAg分布在感染的戴恩颗粒(Dane particle)表面,是参与乙型肝炎感染的免疫应答的抗原。绝大多数的片段直径为20 nm,长度可变。到目前为止,大部分存在的HBsAg都是小的、非感染性的20 nm的颗粒5。
Figure1. Surface antigen of the hepatitis B virus
参考文献:
1.Le Bouvier, G. L., Mccollum, R. W., Hierholzer, W. J., Irwin, G. R., Krugman, S. & Giles, J. P. (1972). Subtypes of Australia antigen and hepatitis-B virus. Journal of the American Medical Association 222, 928-930
2.Courouce-Pauty, A. M., Plancon, A. & Soulier, J. P. (1983). Distribution of HBsAg subtypes in the world. Vox sanguinis 44, 197-211.
3.Yamashita, Y., Kurashina, S., Miyakawa, Y. & Mayumi, M. (1975). South-to-north gradient in distribution of the r determinant of hepatitis B surface antigen in Japan. Journal of Infectious Diseases 131, 567-569.
4.A. M. Moriarty, B. H. Hoyer et al. Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector. Proc. Nati. Acad. Sci. 78: 2606-2610(1981).
Figure1. Surface antigen of the hepatitis B virus
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 899.13 |
Formula | C46H74N8O10 |
Synonyms | H2N-Ile-Leu-Ser-Pro-Phe-Leu-Pro-Leu-OH |
Solubility | ≥89.9 mg/mL in DMSO; ≥25.05 mg/mL in H2O; ≥49.8 mg/mL in EtOH |
SDF | Download SDF |
Canonical SMILES | NC(C(C)CC)C(NC(C(NC(CO)C(N1CCCC1C(NC(CC2=CC=CC=C2)C(NC(CC(C)C)C(N3CCCC3C(NC(C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)CC(C)C)=O |
运输条件 | 蓝冰运输或根据您的需求运输。 |
一般建议 | 不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存,请尽快用完。 |
质量控制和MSDS
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