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Recombinant Human PTH1-84

 
Catalog No.
P1224
重组人甲状旁腺激素1-84(PTH1-84)
组合的产品项目
规格价格库存 数量
10X10ug
¥ 3,659.00
Ship with 5-10 days
50X10ug
¥ 8,209.00
Ship with 5-10 days

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A

背景

甲状旁腺激素 (PTH) 是一种由 84 个氨基酸组成的单一多肽。 PTH 是调节 Ca2+ 稳态的关键激素。 PTH由甲状旁腺分泌,通过激活成骨细胞和抑制破骨细胞,促进钙从骨释放到细胞外液,间接促进肠道对钙的吸收增加,并促进肾小管对钙的重吸收和肾对磷酸盐的排泄增加。它是骨代谢的主要调节剂。当细胞外液中的钙水平较低时,甲状旁腺激素的分泌就会增加。

Reference

[1]. Potts, J.T. 2005. J Endocrinol, 187: 311-25.

[2]. Misiorowski, W. 2011. Endokrynol Pol, 62: 73-8.

[3]. Scillitani, A., V. Guarnieri, C. Battista, et al. 2011. J Endocrinol Invest, 34: 23-6

Information

Accession #P1224
Alternate NamesParathormone, Parathyrin
SourceEscherichia coli.
Protein sequenceSVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNFVALGAP LAPRDAGSQR PRKKEDNVLV ESHEKSLGEA DKADVNVLTK AKSQ
M.Wt9.4 kDa
AppearanceSolution protein
Stability & Storage

Avoid repeated freeze-thaw cycles

It is recommended that hat the protein be aliquoted for optimal storage

- 12 months from date of receipt, -20 to -7°C as supplied

Concentration0.1-1.0 mg/mL
FormulationDissolved in Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. This solution can be diluted into other aqueous buffers.
Biological ActivityFully biologically active when compared to standard. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of > 2.0×104 IU/mg.
Shipping ConditionThe product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
HandlingCentrifuge the vial prior to opening.
UsageFor Research Use Only! Not to be used in humans.

质量控制

质量控制和DataSheet

批次:
    纯度 > 97 % by SDS-PAGE and HPLC analyses.
    Endotoxin: <1 EU per 1 ug of the protein by the LAL method.
  • Datasheet