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Recombinant Human GH

 
Catalog No.
P1223
重组人生长激素(GH)
组合的产品项目
规格价格库存 数量
10X10ug
¥ 1,950.00
Ship with 5-10 days
50X10ug
¥ 4,374.00
Ship with 5-10 days

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A

背景

生长激素 (GH),也称为生长激素,是生长因子家族的一员,其中包括催乳素、胎盘催乳素、增殖素和生长激素。它是一种肽激素,可刺激人类和其他动物的生长、细胞繁殖和再生。生长激素是一种由 191 个氨基酸组成的单链多肽,由垂体前叶侧翼内的生长细胞合成、储存和分泌。 GH 脉冲式释放到循环中受到下丘脑激素 - GH 释放激素 (GHRH) 和生长抑素 (SST) 的协同作用以及来自外周的信号 - 生长素释放肽和瘦素的调节。人类 GH cDNA 编码 217 个氨基酸 (aa) 残基的前体蛋白,以及 26 个氨基酸的推定信号肽。通过选择性剪接,至少四种 GH 亚型已被鉴定。

Reference

[1]. Goffin, V., K.T. Shiverick, P.A. Kelly, et al. 1996. Endocr Rev, 17: 385-410.

[2]. Tannenbaum, G.S., W. Gurd, and M. Lapointe. 1998. Endocrinology, 139: 3871-5.

[3]. Welniak, L.A., R. Sun, and W.J. Murphy. 2002. J Leukoc Biol, 71: 381-7.

Information

Accession #P1223
Alternate NamesGH1, GH, GHN, GH-N, hGH-N,Pituitary Growth Hormone, Growth Hormone 1, Somatotropin.
SourceEscherichia coli.
Protein sequenceFPTIPLSRLF DNAMLRAHRL HQLAFDTYQE FEEAYIPKEQ KYSFLQNPQT SLCFSESIPT PSNREETQQK SNLELLRISL LLIQSWLEPV QFLRSVFANS LVYGASDSNV YDLLKDLEEG IQTLMGRLED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY GLLYCFRKDM DKVETFLRIV QCRSVEGSCG F
M.Wt22 kDa
AppearanceSolution protein
Stability & Storage

Avoid repeated freeze-thaw cycles

It is recommended that hat the protein be aliquoted for optimal storage

- 12 months from date of receipt, -20 to -7°C as supplied

Concentration0.1-1.0 mg/mL
FormulationDissolved in Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA.
ReconstitutionWe recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. This solution can be diluted into other aqueous buffers.
Biological ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat Nb2-11 lymphoma cells is less than 0.1 ng/ml, corresponding to a specific activity of > 1.0×107 IU/mg.
Shipping ConditionThe product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
HandlingCentrifuge the vial prior to opening.
UsageFor Research Use Only! Not to be used in humans.

质量控制

质量控制和DataSheet

批次:
    纯度 > 98 % by SDS-PAGE and HPLC analyses
    Endotoxin: <1 EU per 1 ug of the protein by the LAL method.
  • Datasheet