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MNS

Catalog No.
A8661
Src/Syk酪氨酸激酶抑制剂
组合的产品项目
规格价格库存 数量
10mM (in 1mL DMSO)
¥ 600.00
现货
5g
¥ 480.00
Ship with 10-15 days

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Background

Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation). Exhibits no effects on Ca2+-dependent enzymes, PKC or arachidonic ac

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt193.16
Cas No.1485-00-3
FormulaC9H7NO4
Solubility≥8mg/mL in DMSO
Chemical Name5-[(E)-2-nitroethenyl]-1,3-benzodioxole
SDFDownload SDF
Canonical SMILESC1OC2=C(O1)C=C(C=C2)C=C[N+](=O)[O-]
运输条件试用装:蓝冰运输。 其他可选规格:常温运输或根据您的要求用蓝冰运输。
一般建议为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次产品溶解度各有差异,仅做参考。若实验所需浓度过大至产品溶解极限,请添加助溶剂助溶或自行调整浓度。

生物活性

Description MNS is an inhibitor of tyrosine kinases with IC50 values of 2.5 μM, 29.3 μM and 1.7 μM for Syk, Src and p97, respectively.
Targets p97 Syk Src      
IC50 1.7 μM 2.5 μM 29.3 μM      

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